Migraine and Clinical Trials – Treating Mental Disturbances Wisely

A severe throbbing pain, usually on one side of the head, is felt in cases of migraine. Nausea and extreme sensitivity to incoming rays of light or high intensity sound accompany migraines. These attacks create a painful impact that may last from hours to days. This pain can turn severe and diminish one’s capacity to think and function.

Migraines might go through four stages:

  • Prodromal stage – 2-3 days prior to the migraine attack, symptoms of thirst, stiffness, constipation, yawning, and mood swings might show up.
  • Attack – Usually lasting anywhere between 4 to 72 hours if untreated, headaches occur at frequencies that vary from person to person.
  • Post-dromal stage – This is the final phase that occurs after the attack. Most people feel drained while some people experience a state of elation.

Causes and Triggers

  • Imbalance of brain chemicals can cause a migraine attack. Serotonin levels drop during these attacks.
  • Fluctuations in oestrogen for women often cause attacks.
  • Salty food or food additives can trigger migraines.
  • Stress, alcohol, physical exertion, and changes in environmental conditions are everyday things that can cause these attacks.

A migraine clinical trial, designed for research, can verify the utility of new drugs that are specifically intended to treat migraines.

For SPRI, the main criterion to be eligible for participating in the trial is mentioned below:

  • Between the range of 18-65 years of age
  • Already diagnosed by a doctor for showing symptoms of migraines
  • Suffering from migraines for at least a year or so
  • Having at least 2 migraine attacks every month over the last 3 months.

It’s recommended for someone suffering from a migraine attack to participate in a migraine clinical trial. Raising awareness about specific treatments can only solve the problems for researchers, doctors and patients alike.

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